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"A NATURAL ENVIRONMENTAL HEALTH FACTS Ezine"
Here to Inform and Help You Become Healthier and Happier while Achieving Quality
Longevity!
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Wednesday May 30, 2007
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=> IN THIS ISSUE!
============================
==> Editors' Ranting & or Warnings
==> Something To Think About
==> Health Thought for the day!
==> Showcase Health Spotlight
==> Monthly Spotlight Ads
==> Today's Health Tip
==> Health Today
==> Environmental Report
==> Life Changing Information
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EDITORS' RANTING
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Something To Think About
============================
CANCER DOCTORS ARE
PAID TO PRESCRIBE DUBIOUS DRUGS!
Procrit, Epogen and Aranesp - known collectively as
epoetins or ESAs (erythropoiesis stimulating agents) - are among the
world's best-selling drugs, with combined sales of $10 billion last
year. In the US, they constitute the single biggest drug expense for
Medicare and are given to about a million patients each year to treat
the anemia that is caused by cancer chemotherapy or by kidney disease.
Two of the world's largest drug companies, Amgen and Johnson & Johnson,
have been paying hundreds of millions of dollars in incentive bonuses to
doctors - including medical oncologists - who prescribe the anti-anemia
drugs.
Procrit and Aranesp can be very effective in correcting the severe
anemia that often accompanies cancer. Epogen is widely used in the
treatment of patients with renal (kidney) failure, another situation in
which anemia is extremely common. Epoetins have been heavily marketed to
both physicians and patients on the basis of their ability to reduce the
need for blood transfusions, give patients more energy and improve their
quality of life. However, there is an emerging downside to the use of
these drugs.
An increasing number of researchers have become concerned that the drugs
may increase a patient's risk of heart attack and strokes. Furthermore,
they do not improve the outcome of cancer treatment. In fact, there is
growing evidence that they may actually shorten, rather than lengthen,
survival. In the light of mounting concern over the dangers of these
drugs, the US Food and Drug Administration (FDA) last month belatedly
cautioned that epoetins may be unsafe at the commonly used dose levels,
and insisted that a "black box" warning be added to the labels and
prescribing information for Aranesp, Epogen and Procrit. In mid-May, an
FDA advisory committee urged that additional restrictions be put on the
use of drugs that treat anemia in cancer patients (Pollack 2007).
The FDA has been very slow to move on the question of epoetin safety.
The first indication that the drugs might in fact be harmful came in
1996. A clinical trial sponsored by Amgen was set up to show that
dialysis patients would benefit from having their hemoglobin raised to
14 g/dL, which is the level in a healthy person But the trial found
instead that patients who were given epoetins to raise their hemoglobin
to 14 g/dL suffered more deaths and heart attacks than a group treated
with a hemoglobin goal of 10 g/dL. The trail was prematurely stopped.
Dr. Anatole Besarab of the Henry Ford Hospital in Michigan, the lead
author of that study, told the Times that Amgen and Johnson & Johnson
had little incentive to conduct a definitive trial.
A full decade elapsed before FDA finally was spurred to act. On March
9th, 2007 it issued an advisory warning that "an increased number of
deaths and of non-fatal heart attacks, strokes, heart failure, and blood
clots [occurred] when ESAs were adjusted to maintain...hemoglobin more
than 12 g/dL" (FDA 2007).
The FDA acknowledged that there is a higher chance of death and an
increased rate of tumor growth when patients with advanced head and neck
cancer who are receiving radiation therapy are given epoetins.
Similarly, in patients undergoing chemotherapy for advanced breast
cancer, epoetins such as Procrit, when given to push their hemoglobin
levels above 12 g/dL, are associated with an increased rate of tumor
progression. In addition, patients scheduled for major surgery who were
given epoetin showed a higher rate of thromboembolism (blood clots).
FDA also says that when epoetins are given to anemic cancer patients who
are not receiving chemotherapy, the need for blood transfusions is not
reduced, and there is actually a higher chance of death. Similarly,
patients with chronic renal failure have a higher chance of death and an
increased risk of blood clots, strokes, heart failure, and heart attacks
when epoetin is given to maintain hemoglobin levels of more than 12 g/dL.
Overall, the FDA has explicitly acknowledged that there is no evidence
to indicate that epoetins such as Procrit, Epogen or Aranesp either
improve patients' quality of life or extend their survival. Meanwhile,
several studies suggest that the drugs actually shorten patients' lives
when used at high doses.
To be concluded, with references, next week.
Ralph W. Moss,
Ph.D.
=======================
THOUGHT FOR THE DAY!
=======================
Historically, the medical profession has shown considerable reluctance
to involve patients fully in the decision making process. During the
1960s, for example, over 90 percent of US physicians indicated that they
felt a patient with cancer should definitely not be told the
nature of his or her disease. Although this secretive and strongly
paternalistic attitude has now largely dissipated - more than 97 percent
of physicians would now unhesitatingly reveal a diagnosis of cancer -
clinicians still often greatly underestimate the amount and type of
treatment information that their patients need to be given. The
constraints of today's managed care system certainly do not help. While
many doctors would almost certainly like to spend more time with
patients to explain things in more depth and answer questions more
fully, the constraints imposed by the increasingly prevalent managed
care system conspire to make the allocated time per visit ever shorter.
The net result is that patients feel unable to make truly informed
decisions. Robbed of the opportunity to discuss their medical needs
thoroughly with their physicians, people often turn to the Internet for
answers. Certainly, the Internet has unlocked the medical libraries and
made vast quantities of formerly unavailable medical literature
accessible to everyone. But it has also made available an abundance of
unreliable information, often couched in pseudo-scientific language,
whose concealed purpose is to sell the unwary a product or service that
is essentially worthless. Care should be taken when evaluating a health
problem!
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We accept all advertisements in good
faith, but the advertisers are completely responsible for the content
and accuracy of their advertisements. We do not give any warranties and
accept no responsibility. The editor and publisher suggest that you
exercise due diligence!
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TODAY'S HEALTH TIP
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Seniors who regularly take aspirin to
prevent strokes could instead actually be increasing their risk.
In healthy older people,
aspirin may very well be doing more harm than good.
Healthy older people who take regular aspirin to prevent
stroke may actually be increasing their risk.
Researchers looked at data on intracerebral hemorrhagic strokes that occurred
between 1981 and 1985, and between 2002 and 2006.
The number of strokes caused by high blood pressure fell by 65 percent over this
period. But in people over 75, so many more strokes occurred among patients
taking blood-thinning drugs such as aspirin and warfarin, known as
antithrombotics, that the overall rate of strokes remained the same.
Between the two periods studied, the proportion of stroke patients on
antithrombotic drugs increased from 4 percent to 40 percent. The number of
strokes associated with these drugs increased by a factor of seven.
The Lancet Neurology May 1, 2007
BBC News May 1, 2007
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HEALTH TODAY
~^~^~^~^~^~^~^~^~^~^~
Study:
Boomers Could Retire in Poorer Health Than Did Elders
־
Undoing the Damage
Bad habits damage our bodies. But take heart ... cleaning up
your act can undo a lot of the harm.
Americans now in their early to mid-50s report poorer health,
more pain and more trouble doing everyday physical tasks than
their older peers reported while at the same age, according to
an analysis from the National Bureau of Economic Research and
supported by the National Institute on Aging.
Researchers from the University of Pennsylvania and Carleton
University compared the overall, self-reported health of people
in three groups -- those born in 1936-1941, 1942-1947 and
1948-1953. The data draws from survey respondents' answers to
questions about their health and well-being when they were all
between the ages of 51 and 56. The study showed:
The two younger groups were less likely to say their health was
"excellent or very good" at 51 to 56 years of age.
The youngest group reported having more pain, chronic health
conditions and drinking and psychiatric problems than people who
were the same age 12 years earlier.
The youngest group was more likely to report difficulty in
walking, climbing steps, getting up from a chair, kneeling or
crouching and doing other normal daily physical tasks.
The analysis raises the question of whether today's pre-retirees
could reach retirement age in poorer health than current
retirees and possibly inaease health care costs for society.
www.nia.nih.gov.
^~^~^~^~^~^~^~^~^~^~^~^~^~^~^
ENVIRONMENTAL REPORT
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Climate Changes Said Harm
Sunflowers
May 19, 2007
KANSAS CITY, Mo. (AP) - Imagine the Sunflower State without its
sunflowers. That's one of the dire predictions contained in a
new report on global warming released by the National Wildlife
Federation, which says the Kansas state flower could move north
to other states in a few decades.
Increasingly warm temperatures also could mean the end of the
state tree, the eastern cottonwood, according to "The Gardener's
Guide to Global Warming."
"Everything being equal, these plants won't thrive and will
shift north," said Patty Glick, the report's author and senior
global warming specialist for the National Wildlife Federation.
While conditions could change, Glick and other say projected
increasing temperatures also could wipe out cool-weather
grasses, such as Kentucky bluegrass, and many fescues that cover
lawns in the region.
Some experts think global warming will cause temperatures in
Kansas to rise an average of 5 to 12 degrees in the next several
decades.
The projection that the sunflower could fade from Kansas'
landscape surprised some experts and scientists.
"This is a plant that has survived for eons," said Dennis
Patton, a horticulturist with the Johnson County Kansas State
University Research and Extension office. "It is hard to believe
in this short period of time that the plant would be
non-existent here. Same with the cottonwood.
"I guess what I come back to, it is a good wake-up call."
John Blair, a Kansas State University professor and research
scientist at the Konza Prairie research station north of
Manhattan, has been conducting experiments for nine years on the
effect of altered rain patterns on plants.
Blair said even if total rainfall doesn't change, computer
models show the rain will come less often and will fall in
strong downpours when it does come.
He is finding that plants with root systems able to reach water
deeper in the earth have a better chance of survival. For plants
in the wild, that means many perennials have a better chance
than annuals such as the sunflower because of their more
developed root systems.
What would the lack of a sunflower mean for Kansas, which has
Mount Sunflower and hundreds of businesses, clubs and
associations with sunflower in their titles?
"Maybe in 100 years the Texas bluebonnet will be the Kansas
state flower," Patton said.
The Wildlife Federation report said the Missouri state tree and
flower - the flowering dogwood and the white hawthorn blossom -
are not endangered.
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