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A Natural Environmental Health Facts Ezine
 Information For Getting Healthy

Lena Sanchez Editor


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 Tobacco is a mood-altering, addictive drug that kills 500,000 Americans a year (200 million worldwide)
Costs $400 billion each year, according to "Smoking and Health Review," (1992). 

The American Lung Association says tobacco contains more than 4,000 chemicals, 60 of which causes cancer. 
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"A NATURAL ENVIRONMENTAL HEALTH FACTS Ezine"  Here to Inform and Help You Become Healthier and Happier while Achieving Quality Longevity!

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Sunday  August 8, 2004
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============================
=> IN THIS ISSUE!
============================


==> Editors' Ranting & or Warnings
==> Something To Think About
==> Thought for the day!
==> Today's Health Spotlight
==> Monthly Spotlight Ads
==> Today's Health Tip
==> Food of The Week
==> Health Today
==> Environmental Report
==> Life Changing Information



+++++++++++++++++++++
EDITORS' RANTING
+++++++++++++++++++++

Greetings and welcome to A Natural Environmental Health Facts ezine.

Today's information looks a bit like drug company bashing but actually I didn't plan it that way I only report what is there and it just happens that these all came up so close together!

I hope you are enjoying your weekend and getting that needed rest and relaxation! Laugh as much as possible!

If you have a question or comment (good or bad) send it to me... Click Here 

Remember ANEH Facts archives now exist  Click Here 

Ask Lena Health Q & A Archives  Click Here

Take charge of you and your family's health before it takes charge of you!
Lena



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Something To Think About
============================

Crestor Side Effect Report Delayed
Aug 3, 2004
 
WASHINGTON (AP) - A drug company illegally delayed reporting side effects linked to its anti-cholesterol drug Crestor, a consumer advocate contended Tuesday in urging a Food and Drug Administration investigation.

It's the latest attack on Crestor by the private group Public Citizen, which argues that Crestor is riskier than its competitors and should be banned.

FDA requires drug makers to reveal reports of serious and unexpected side effects within 15 days of learning about them. While those reports don't prove a drug was to blame, FDA evaluates them to determine whether a medicine is riskier than initially thought.

Public Citizen's Dr. Sidney Wolfe charged that AstraZeneca delayed its reports to the FDA by as long as 97 days. The company ultimately reported that 19 Crestor users suffered an often life-threatening muscle-destroying condition - and filed four reports of kidney failure.

The delays "have unquestionably impaired FDA's ability to promptly assess the safety of this uniquely dangerous drug," Wolfe wrote FDA Acting Commissioner Lester Crawford Tuesday.

AstraZeneca insists that Crestor is no more risky than other cholesterol-lowering "statin" drugs, and that it followed FDA rules. The company says it wasn't subject to the 15-day deadline because the side effects were mentioned on the drug's label.

Wolfe countered that Crestor's label implies the muscle-destroying side effect occurs only with an unapproved high dose. The company's own reports, however, implicate far lower doses. The drug's label only mentions kidney failure in passing, Wolfe said.

FDA hasn't formally determined whether AstraZeneca should meet the 15-day deadline, said Dr. Mary Parks, medical officer.

So far, the agency says it sees no signal that Crestor is riskier than other statins, which all can cause rare cases of the muscle side effect.

http://www.astrazeneca.com/  
 


=======================
THOUGHT FOR THE DAY!
=======================


Ulcer Treatments Recommendations Changed!
 
Years ago, if you had an ulcer, you were put on a strictly bland diet.

Now that antibiotics and drugs reduce stomach acid, where does the bland diet stand?

According to the journal, Medical Clinics of North America, milk and milk products -- a basic part of the ulcer diet -- are not recommended. Milk neutralizes gastric acid, but only for a short time. When the effect wears off, the acid comes back worse than before.

Most spices, particularly black pepper and red pepper, which can cause an upset stomach, should still be avoided. But chili powder, on the other hand, seems to be safe.

Take it easy on alcoholic beverages, which increase stomach acid. High concentrations of alcohol, around 80 proof, are the worst. Stick with beer and wine.

Avoid coffee, including decaf, which stimulates gastric acid.
 


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 TODAY'S HEALTH TIP

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Secret US report surfaces on antidepressants in children
Jeanne Lenzer

Internal memos and a secret government report about the negative effects of antidepressants in children-suppressed by the US Food and Drug Administration-have surfaced publicly.

The Alliance for Human Research Protection, a national network dedicated to ensuring ethical standards in medical research, published the documents on 26 July.

The published documents confirm earlier news accounts that a government expert with the FDA's Office of Drug Safety, Dr Andrew Mosholder, found that children taking antidepressants were twice as likely to become suicidal as children taking placebo. He reportedly urged the agency to follow the lead of British health authorities by warning doctors that the risks of the newer antidepressants, except fluoxetine, might outweigh the benefits when used in children.

The leaked documents show his data and conclusions. The FDA has subsequently acknowledged to the BMJ that Dr Mosholder was prevented from presenting his report at an advisory committee meeting on 2 February and was told that if he was asked any questions during the meeting he could respond to queries only by using a prepared script approved by his supervisors.

Dr Mosholder had evaluated data from 22 studies using nine drugs in 4250 children and found that 74 of the 2298 children taking antidepressants had a "suicide related event" compared with 34 of the 1952 children taking placebos.

When questioned about the decision to suppress Dr Mosholder's report, Dr Robert Temple, associate director for medical policy in the FDA's drug evaluation centre, defended the agency's actions. "We thought the analysis was premature," he told the BMJ.

Both the raw data and Dr Mosholder's interpretation were "imperfect" said Dr Temple, adding that some of the behaviours labelled "suicidal" were highly suspect and could have been accidents, such as a child "who hit her head with her hand." FDA officials acknowledged, however, that some cases classified as "accidental injury" could be suicide related. Because of this, the FDA has contracted with Columbia University to further study and classify events that might be considered to be suicide related.

Some of these events, he added, such as superficial cutting, "might be due to anxiety" and not represent true suicidal intent.

Dr Thomas Laughren, the FDA's team leader for psychiatric drug products, told the BMJ that he had reported the relative risk ratios of all the drugs evaluated at the advisory meeting and that it was Dr Mosholder's conclusions, and not the data, that were withheld.

Responding to critics who say studies of antidepressants other than fluoxetine show little or no efficacy in children, Dr Temple said absence of proof should not be interpreted to mean the drugs are ineffective.

Dr Jerome Hoffman, an epidemiologist and professor of medicine at the University of California at Los Angeles, told the BMJ that the flip side of Dr Temple's claim that antidepressants in children could be life-saving is that they could be life threatening-as suggested by Dr Mosholder's report.

"Most Americans undoubtedly believe that the FDA demands reasonable evidence that a drug is safe before it is allowed to be used," said Professor Hoffman. "But this episode suggests that they reject this `precautionary principle' in favour of the idea that no drug is dangerous unless it is `proven' to be so."

"The FDA... attempted to silence Dr Mosholder [but] repeatedly claimed to `support his concern' for the safety of children," added Professor Hoffman, "but this apparently didn't extend to supporting his desire to express that concern publicly. That may be the most dangerous aspect of this entire affair."

The FDA has launched a criminal investigation to find out which employees leaked Dr Mosholder's report. Meanwhile the suppression of the report has triggered Congressional investigations by Senator Charles Grassley, who has interviewed employees in the agency's Office of Drug Safety, where Dr Mosholder worked.
BMJ Journals
 



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FOOD OF THE WEEK
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The Really Healthy Disease Proofing Vegetable!
 
Over the last weeks, if you've read all the Food Of The Week columns you can see how fruits and vegetables are disease fighters extraordinaire! This week isn't going to change that and in fact is one of the best yet.

I advocate eating at least 50% to 60% of your foods as raw fruits and vegetables daily to get the maximum nutritional value out of them.
 
When it comes to nutritional value, broccoli is at the top. It is rich in vitamins, high in fiber, low in calories and contains as much calcium as milk and much healthier. By including broccoli regularly in your diet you can reduce and prevent ailments like cancer, diabetes, osteoporosis and heart disease.
 
Want to know how to beat prostate cancer? Your physician will probably tell you to take prescription drugs. That's the pharmaceutical industry trained doctor's answer who has been brainwashed to give that answer. For a dual killer of those nasty illnesses mix tomato and broccoli, and even helps reverse breast cancer, colon cancer, leukemia and other cancers of the body.
 
Why not something that is safer that your body is built to accept 100% and is proving to be far better for fighting diseases.
 
This green vegetable looks like a bush should be on everyone's plate on a regular basis, if they wish to stay healthy! Has been around for more than 2000 years. During the 16th century, the plant was grown in Italy and France. It began to be commercially grown in the United States in the 1920s. The word "broccoli" derives from the Italian 'Brocco' meaning arm branch. Broccoli is related to cabbage, cauliflower and Brussels sprouts.
 
Broccoli is an antioxidant rich food filled with the minerals Calcium, Iron, Magnesium, Phosphorus, Potassium, Sodium, Zinc, Copper, Manganese and Selenium. Rich in vitamins such as; Vitamin C, Thiamin, Riboflavin, Niacin, Pantothenic acid, Vitamin B-6, Folate, Folic acid, Vitamin B-12, Vitamin A, Retinol and Vitamin E.  broccoli really delivers in the nutrition department. 
 
A University of Illinois-Urbana study found that rats eating a combination of broccoli and tomatoes had a lower rate of tumor growth than rats eating broccoli or tomatoes separately.  Researcher John Erdman said the two foods bring out the best in each other, and maximize the cancer-fighting effect of the nutrients they contain. You might consider mixing the two for optimum illness fighters!
 
When choosing broccoli in the market, select organic heads that have tight and compact bud clusters with an even dark color. The stems should be a lighter green than the buds and easy to pierce with a fingernail. Avoid stalks with yellowed or open bud clusters and stems that are hard and dry. Broccoli can be stored, unwashed, in a plastic bag in the refrigerator crisper for days. Before use, wash by rinsing in purified/filtered water with a splash of vinegar for disinfectant. 
 
Our favorite ways of eating broccoli are steamed with a splash of seasoned rice vinegar, or raw with other veggies as a salad with lemon juice and virgin olive oil or flax seed oil as dressing. Also we like raw broccoli flowerets with sliced tomatoes and sliced sweet onions. Grandchildren like them with a bit of ranch dressing, which I don't think of as healthy but a little once in a while isn't going to kill them and it gets them to eat the broccoli! I try to make it fresh so it's not quite as lethal.
 
Here is a great recipe:
 
Broccoli with Garlic
 
1 bunch of broccoli, OR 1 pound of frozen chopped broccoli
2 medium fresh tomatoes (cut into bite size pieces)
6 garlic cloves 
1 to 2 tablespoons olive oil
1/2 teaspoon sea salt
2 tablespoons purified/filtered water
1/4 teaspoon hot (cayenne) pepper (optional)
 
Wash broccoli and cut into small florets.   Cut the tender parts of the stem into smallish cubes or save add to stew or make Broccoli Slaw.
 
Steam in a microwave steamer or over boiling water until barely tender and still bright green (about 3-1/2 to 5 minutes in a microwave, depending on the volume of broccoli and water).  Don't overcook!  For all cruciferous, this is a very important guideline!
 
Place olive oil in a skillet over medium heat.  Chop or mince the garlic.   When the oil is hot, add the salt, then the garlic.  Saut? stirring frequently, just until the garlic starts to soften.  Quickly add the water, and the cayenne if desired.  Turn heat low and simmer for a couple of minutes.
 
Place the broccoli and fresh tomatoes in a large glass or crockery serving bowl.  Pour the garlic mixture over it, mixing gently to coat each piece evenly.  Serve and enjoy.

 
Chill leftovers and add to salad the next day.
 
Now go get some broccoli for your next meal, enjoy and know you are eating for health!

Lena



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HEALTH TODAY

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Study: Heart Drug Use Resulted in Deaths
By STEPHANIE NANO

NEW YORK (AP) - New research shows that soon after doctors started prescribing a drug for congestive heart failure more widely, the number of patients who died from a side effect increased.

The researchers say their findings illustrate what can happen when doctors apply drug-study results to their own patients. They suggest that some of the patients probably shouldn't have been given the heart failure drug and that doctors weren't checking for dangerous potassium buildup.

"I have no doubt that in the right patients and with careful monitoring that this is still a good drug combination," said Dr. David N. Juurlink, one of the Canadian researchers. "It's just when we prescribe it more widely and maybe we don't monitor patients quite as closely as we should, then that's where we get into trouble."

Juurlink and others believe the same thing is happening in the United States as in Canada where the study of the decades-old drug, spironolactone, was conducted.

A major study five years ago found that adding spironolactone to the standard treatments cut the death rate by 30 percent in people with serious heart failure.

The new study looked at what happened after that, when doctors put more patients on the medicine. It was done by the Institute for Clinical Evaluative Sciences, a health care research organization in Toronto, and is reported in Thursday's New England Journal of Medicine.

"It's a caution that all the safeguards that are in place in a controlled clinical trial are not present out in practice," said Dr. Biff Palmer of the University of Texas Southwestern Medical School in Dallas, who wrote a related journal article on preventing and treating high potassium.

About 5 million Americans have heart failure, which occurs when a weakened heart can't pump enough blood throughout the body, causing swelling and fluid to back up in the lungs.

Spironolactone, also known as Aldactone, helps the kidneys get rid of excess water and salt but can lead to potassium buildup in the blood. High levels can cause irregular heartbeats or sudden death.

The Canadian researchers examined whether the use of spironolactone had increased after the 1999 research, and what impact it was having on patients who take a standard ACE inhibitor and had been sick enough to be recently hospitalized. ACE inhibitors relax the blood vessels and lower blood pressure but can contribute to high potassium when combined with spironolactone.

The researchers tracked prescription and hospital records from 1994-2001 for about 1.3 million residents of the province of Ontario who were over 65.

"We found when the drug took off in mid-1999, so did rates of hospitalization for high potassium and deaths in hospital associated with that," said Juurlink.

Prescription rates for spironolactone increased fivefold, and hospitalizations and deaths from high potassium tripled. The number of heart patients hospitalized jumped from 4 to 11 per 1,000; deaths rose from 0.7 to 2 per 1,000.

In Ontario alone, researchers estimated that broader use of spironolactone resulted in 73 additional hospital deaths and 560 more hospitalizations in 2001 than would have been expected.

They said that would correspond to about 4,200 more deaths from high potassium and 37,000 more hospitalizations a year in the United States when applied to patients with milder heart failure.

Researchers think doctors may have prescribed higher doses than needed or given the drug to patients with other ailments like diabetes and kidney problems that could put them at higher risk for high potassium. Palmer said doctors should ask about over-the-counter drugs, herbal remedies and foods that could contribute to potassium problems.

Dr. Willem Remme, who helped conduct the 1999 study, said he is glad that doctors are prescribing spironolactone but they need to pay attention to how it was used in the study.

"This reflects the lack of education of doctors, I think, and that's what worries me most," said Remme, director of the Sticares Cardiovascular Research Institute in the Netherlands.

New England Journal
American Heart Association 

 

 


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    ENVIRONMENTAL REPORT      
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Feds Accused of Exaggerating Fire Impact
By SCOTT SONNER
 
MOSQUITO RIDGE, Calif. (AP) - The Forest Service exaggerated the effect of wildfires on California spotted owls in justifying a planned increase in logging in the Sierra Nevada, according to a longtime agency expert who worked on the plan.

Other wildlife biologists inside and outside the Forest Service confirm that at least seven of 18 sites listed by the agency as owl habitat destroyed by wildfires are green, flourishing and occupied by the rare birds of prey.

The new disclosures - in interviews with The Associated Press, tours of the areas in question and reviews of hundreds of pages of documents - raise new questions about the agency's conclusion in January that significantly more logging of bigger trees must be allowed to protect the region's oldest forests.

The Forest Service's claim that an average of 4.5 owl sites a year have been lost to Sierra wildfires over the past four years is included in a plan to reduce wildfire threats and in a controversial agency brochure. The "Forests with a Future" brochure already is under fire from some members of Congress and others who say the agency misrepresented forest conditions in California by substituting photographs from Montana.

"I'm real uncomfortable with the constant portrayal of fire in the environment as a negative thing - all hellfire and brimstone," said Michael Gertsch, a Forest Service wildlife biologist since 1976. Gertsch said he was removed last year from the team that wrote the plan to manage the 11 national forests in the Sierra Nevada after he complained repeatedly about the agency's mischaracterization of the effect fires have on the owl, which is dependent on old stands of trees.

An important statement that put fire threats in perspective was stricken from the final version of the plan published in January, Gertsch told The Associated Press.

"It was dropped because the conclusion of my analysis was that fire appears to be more of a maintenance mechanism than a destructive force for owl habitat," said Gertsch, who works as the agency's Pacific Southwest regional coordinator of threatened and endangered species.

"The only reason the revisions were made was to allow logging of bigger trees," said Chad Hanson, director of the John Muir Project, which is appealing the plan to Forest Service Chief Dale Bosworth. "It was a gift to the timber industry."

Forest Service regional spokesman Matt Mathes said any discrepancies between the data used to calculate effects on owls and forest conditions are due to outdated figures "and not an intentional attempt to mislead."

"We went with what we knew at the time. They were lost at the time the draft went out. Things change on the ground," Mathes said.

An AP tour of two owl habitat sites reported destroyed by fire according to the Forest Service showed mostly green forests. In the worst case, about one-third the forest area had burned. Forest Service biologists confirmed one of the sites remained inhabited by spotted owls and acknowledged the other could support the birds.

The same seems true across much of the Sierra, according to agency experts and others.

A wildlife biologist who surveyed owl sites for the Forest Service near Lake Tahoe from 1999 to 2001 said her visits to six of 18 Sierra sites the agency lists as lost to fire since 1999 found mostly green stands capable of supporting the owls, including several occupied by the birds.

Two Forest Service biologists in the field confirmed all three sites labeled "lost" in the Tahoe National Forest are occupied by owls. The agency's regional office apparently mischaracterized the situation based on mistaken or outdated data, they said.

A third said the same is true of an owl site in the Eldorado National Forest west of Lake Tahoe, and a fourth said the same thing about at least three owl sites listed as "lost" at the Plumas National Forest 50 miles northwest of Reno, Nev.

"They are not lost. We had owl surveys conducted after the burn and were able to put owls at each one," said Gary Rotta, a biologist for the Plumas National Forest's Mount Hough District.

Mathes acknowledged owls may inhabit some of the sites - which are typically 300 to 400 acres - but he insisted that won't last for long.

Sometimes they remain "among black stems for as long as two years after a wildfire goes through. But eventually the owls do leave," Mathes said.

"You and I could live in a cardboard box on the sidewalk for a certain amount of time. But not for long and you almost certainly wouldn't create offspring."

Critics said the agency is intentionally exaggerating the fire impacts to build a case for more logging.

"It's a really twisted argument," said Monica Bond, the biologist who surveyed owls for the Forest Service at the Eldorado and Tahoe national forests and now works for the Center for Biological Diversity, another conservation group appealing the plan.

"They are using concerns over the owl and concerns about loss of habitat as justification to do more logging of the habitat," she said.

"The claims that fire is eliminating spotted owl habitat in the Sierra Nevada does not appear to be based on any surveys or site-specific analysis of owl survival and occupancy."

The Forest Service first cited a decline in spotted owl nests due to fires in 2003 when agency officials under the Bush administration announced plans to revamp the Clinton-era forest strategy. The Clinton plan had made most of the Sierra's remaining old-growth forests off limits to logging.

But the agency said that policy no longer was workable because of increased fire dangers and revised it to allow for up to a tripling of logging levels to thin the overly dense stands and protect communities and wildlife.

Jack Blackwell, the Forest Service's regional boss in charge of the new plan, cited the loss of owl habitat in issuing the amended version Jan. 22. It's currently before Bosworth, who is considering a number of administrative appeals filed by environmentalists.

"Large, old trees, wildlife habitat, homes and local communities will be increasingly destroyed unless the plan is improved," Blackwell said, specifically citing the recent loss of owl habitat.

Timber industry leaders and their allies in Congress cheered the move.

"The Forest Service is taking steps to reform the outdated management policies left in place by the Clinton administration," said Rep. Richard Pombo, R-Calif., chairman of the House Resources Committee.

"The plan recognizes fire is the single greatest threat to communities, endangered species like the California spotted owl and the overall health of the forests," he said.

The California Forestry Association, though still critical of some parts, agreed the changes "would protect the largest amount of wildlife habitat from current wildfire threats."

Bosworth is to rule before the end of the year on the administrative challenges.

Gertsch said the new plan was a flawed process in comparison to Clinton administration forest rules he helped write and which were adopted in the closing days of the administration.

"Snippets were taken from science, but they didn't listen to the science community," Gertsch said. Communities also were not involved in the process, he said.

"I fought and fought and fought and fought and finally they used some excuse and removed me from the team," he said.

Mathes said he cannot discuss "personnel issues or transfers." Agency documents frequently are revised between draft and final stages, he said.

"We are like any other large organization. We have a diversity of professional opinion," Mathes said.

Jerry Franklin, a University of Washington forester who played a lead role in developing plans to protect the northern spotted owl in the 1990s, is among the prominent scientists who has spoken out against the changes.

"I believe it is a major step back from the ecologically sound approach that had been adopted," Franklin said.

"These large trees of fire resistant species are needed for both fire resiliency and as habitat," he said.

Regardless of criticism and discrepancies in the plan, the agency stands behind its conclusion that more logging is needed to protect the owls.

"Whether or not there is a mix-up or a simple error, our thought process in reaching the decision was not based only on what has happened but what will happen in the future," Mathes said.

"Fires are getting bigger and hotter," he said. Owl habitat has been destroyed and "we expect that trend to continue in the future, perhaps even accelerate, if we don't take some action to change the density of the forest."

U.S. Forest Service: http://www.fs.fed.us/r5/
John Muir Project: www.johnmuirproject.org
Center for Biological Diversity: http://www.biologicaldiversity.org/swcbd/


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